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The Major PGD Milestones:

  • 1968:
    Sexing of Rabbit Embryos at the Blastocyst Stage


  • 1978:
    Birth of the First IVF Baby


  • 1990:
    Sexing Human Preimplantation Embryo, & Polar Body Analysis for Mendelian Disease; First PGD Baby Born


  • 1993:
    FISH Analysis for Sexing and for PGD of Aneuploidies


  • 1996:
    PGD for Chromosomal Translocations


  • 1999:
    PGD for Late Onset Common Disorders with Genetic Predisposition


  • 2000:
    Preimplantation HLA Typing


  • 2002:
    First Thousand PGD Babies Born (see Figure 1)


  • 2009:
    PGD for Chromosomal Disorders by Microarray-Based Technology


  • 2013:
    Next Generation Sequecing for Preimplantation Aneuploidy Testing


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